CD166 Protein (His tag)
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- 抗原 See all CD166 (ALCAM) 蛋白
- CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CD166 protein is labelled with His tag.
- 原理
- Recombinant Mouse ALCAM/CD166 Protein (His Tag) (Active)
- 序列
- Met 1-Lys 527
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Lys 527) of mouse ALCAM (NP_033785.1) precursor was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 98 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Immobilized mouse ALCAM-His at 10 μg/ml (100 μl/well) can bind mouse CD6-Fc, The EC50 of mouse CD6-Fc is 0.08-0.18 μg/ml.
- Top Product
- Discover our top product ALCAM 蛋白
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Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-526) protein (Fc Tag)
ALCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-526) protein (His-Avi Tag,Biotin)ALCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-526) protein (His tag)ALCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) protein (His tag)ALCAM 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) protein (His tag)ALCAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 1-133) protein (GST tag)ALCAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-527) protein (His-Avi Tag,Biotin)ALCAM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-526) protein (His tag,Biotin)ALCAM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Activated Leukocyte Cell Adhesion Molecule (ALCAM) protein (Fc Tag)ALCAM 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-137) protein (GST tag)ALCAM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
- 别名
- ALCAM/CD166 (ALCAM 产品)
- 别名
- CD166 Protein, MEMD Protein, ALCAM Protein, BEN Protein, DM-GRASP Protein, JC7 Protein, SC1 Protein, AI853494 Protein, MuSC Protein, alcam Protein, cd166 Protein, memd Protein, fb53h09 Protein, fb80a10 Protein, nlcam Protein, si:ch211-190h2.4 Protein, wu:fb53h09 Protein, wu:fb80a10 Protein, wu:fc14b01 Protein, activated leukocyte cell adhesion molecule Protein, activated leukocyte cell adhesion molecule a Protein, activated leukocyte cell adhesion molecule L homeolog Protein, CD166 antigen homolog Protein, activated leukocyte cell adhesion molecule b Protein, ALCAM Protein, Alcam Protein, alcama Protein, alcam.L Protein, alcam Protein, cd166 Protein, alcamb Protein
- 背景
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Background: Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target.
Synonym: AI853494, BEN, CD166, DM-GRASP, MuSC, SC1,CD166 antigen,cluster of differentiation 166, CD166, activated leucocyte cell adhesion molecule, CD6 ligand, Protein DM-GRASP,CD6L,MEMD
- 分子量
- 57.7 kDa
- NCBI登录号
- NP_033785
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