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CD166 Protein (Fc Tag)

ALCAM 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320462
发货至: 中国
  • 抗原 See all CD166 (ALCAM) 蛋白
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    蛋白类型
    Recombinant
    宿主
    • 15
    • 11
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    资源
    • 15
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    人细胞
    标记
    This CD166 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse ALCAM/CD166 Protein (Fc Tag)
    序列
    Trp28-Lys527
    产品特性
    Recombinant Mouse Activated Leukocyte Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Trp28-Lys527 is expressed with a Fc tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ALCAM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    别名
    ALCAM/CD166 (ALCAM 产品)
    别名
    CD166 Protein, MEMD Protein, ALCAM Protein, BEN Protein, DM-GRASP Protein, JC7 Protein, SC1 Protein, AI853494 Protein, MuSC Protein, alcam Protein, cd166 Protein, memd Protein, fb53h09 Protein, fb80a10 Protein, nlcam Protein, si:ch211-190h2.4 Protein, wu:fb53h09 Protein, wu:fb80a10 Protein, wu:fc14b01 Protein, activated leukocyte cell adhesion molecule Protein, activated leukocyte cell adhesion molecule a Protein, activated leukocyte cell adhesion molecule L homeolog Protein, CD166 antigen homolog Protein, activated leukocyte cell adhesion molecule b Protein, ALCAM Protein, Alcam Protein, alcama Protein, alcam.L Protein, alcam Protein, cd166 Protein, alcamb Protein
    背景

    Background: Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM interacts with high affinity with CD6 Molecule but weaker homotypic (ALCAM-ALCAM) interactions have also been described. ALCAM-CD6 interactions play an important role in the maintenance of T cell activation, proliferation as well as in formation of immune synapse between antigen-presenting cell and lymphocytes. ALCAM is expressed on a wide variety of cells, particularly on activated lymphocytes, dendritic cells and monocytes, and on various epithelial cell types. It is also involved in multiple processes including embryogenesis, hematopoiesis, angiogenesis, and immune response. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells in most adult tissues. Recently studies showed ALCAM has prognostic relevance in several human carcinomas, and it has been used as a biomarker for several tumor entities, including melanoma, gynecologic, urologic, and gastrointestinal cancers.

    Synonym: AI853494, BEN, CD166, DM-GRASP, MuSC, SC1,CD166 antigen,cluster of differentiation 166, CD166, activated leucocyte cell adhesion molecule, CD6 ligand, Protein DM-GRASP,CD6L,MEMD

    分子量
    83.3 kDa
    NCBI登录号
    NP_033785
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