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CD166 Protein (AA 28-527) (His tag)

ALCAM 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273814
发货至: 中国
  • 抗原 See all CD166 (ALCAM) 蛋白
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    蛋白类型
    Recombinant
    产品特性
    AA 28-527
    宿主
    • 15
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Cynomolgus
    资源
    • 14
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD166 protein is labelled with His tag.
    原理
    Cynomolgus ALCAM/CD166 Protein
    序列
    Trp28-Lys527
    产品特性
    Recombinant Cynomolgus ALCAM/CD166 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Trp28-Lys527.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus ALCAM, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-ALCAM Antibody, hFc Tag with the EC50 of 0.62μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product ALCAM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    别名
    ALCAM (ALCAM 产品)
    别名
    CD166 Protein, MEMD Protein, ALCAM Protein, BEN Protein, DM-GRASP Protein, JC7 Protein, SC1 Protein, AI853494 Protein, MuSC Protein, alcam Protein, cd166 Protein, memd Protein, fb53h09 Protein, fb80a10 Protein, nlcam Protein, si:ch211-190h2.4 Protein, wu:fb53h09 Protein, wu:fb80a10 Protein, wu:fc14b01 Protein, activated leukocyte cell adhesion molecule Protein, activated leukocyte cell adhesion molecule a Protein, activated leukocyte cell adhesion molecule L homeolog Protein, CD166 antigen homolog Protein, activated leukocyte cell adhesion molecule b Protein, ALCAM Protein, Alcam Protein, alcama Protein, alcam.L Protein, alcam Protein, cd166 Protein, alcamb Protein
    背景
    Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.
    分子量
    57.10 kDa. Due to glycosylation, the protein migrates to 70-85 kDa based on Tris-Bis PAGE result.
    UniProt
    G7NZQ8
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