This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
原理
SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag
序列
Met 1 - Ala 419
特异性
SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C)
产品特性
SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). Mutations P13L, R203K, G204R, G214C were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).
SARS-CoV-2 N
宿主: SARS Coronavirus-2 (SARS-CoV-2)
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
应用备注
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition due to glycosylation.
Synonyms: Nucleocapsid protein,NP,Protein N, Description: Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.