SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (G204R, R203K) (His tag)
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- 抗原 See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) 蛋白
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- G204R, R203K
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宿主
- SARS Coronavirus-2 (SARS-CoV-2)
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资源
- HEK-293 Cells
- 标记
- This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
- 原理
- SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag
- 序列
- AA 1-419
- 产品特性
- SARS-CoV-2 Nucleocapsid protein (R203K, G204R), His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1 (R203K, G204R). The nucleocapsid protein is consisted of the N-terminal RNA-binding domain (NTD) and the C-terminal dimerization domain (CTD), divided by a central serine/arginine-rich (SR)-linker responsible for phosphorylation. The mutations (R203K, G204R) were identified on the SR-linker on the nucleocapsid protein of SARS-CoV-2 variants. Phosphorylation of this SR-link motif in SARS-CoV modulates nucleocapsid multimerization, translational inhibitory activity and cellular localization. The co-occuring mutations R203K and G204R may decrease the overall structural flexibility of SARS-COV-2 N protein.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 N 蛋白
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SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 1-419) protein
SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: Mammalian Cells Recombinant Greater than 85 % as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) protein (His tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) protein (His tag,AVI tag,Biotin)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. SDS, ELISA
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 243-364) protein (His-Avi Tag,Biotin)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 64-180) protein (His-Avi Tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 1-419) protein (His tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: CHO Cells Recombinant >95 % as determined by SDS-PAGE and HPLC
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 1-419) protein (His-SUMOstar Tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 酵母菌 Recombinant Greater than 90 % as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (AA 1-419) protein (His-PDI Tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 酵母菌 Recombinant Greater than 85 % as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) protein (His tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE.
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) (T205I) (Active) protein (His tag)SARS-CoV-2 N 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- 别名
- SARS-CoV-2 Nucleocapsid protein (SARS-CoV-2 N 产品)
- 别名
- nucleocapsid phosphoprotein Protein, N Protein
- 物质类
- Viral Protein
- 背景
- Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
- 分子量
- 47.4 kDa
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