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CLEC4C Protein (His tag)

MALS verified CLEC4C 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN7199198
发货至: 中国
  • 抗原 See all CLEC4C products
    CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 3
    资源
    • 5
    • 2
    HEK-293 Cells
    标记
    This CLEC4C protein is labelled with His tag.
    原理
    Human CLEC4C / BDCA2 Protein, His Tag (MALS verified)
    序列
    Asn 45 - Ile 213
    产品特性
    Human CLEC4C, His Tag (CLC-H5245) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    质量等级
    MALS verified
  • 应用备注
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-40 kDa under reducing (R) condition due to glycosylation.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
    别名
    CLEC4C / BDCA2 (CLEC4C 产品)
    别名
    BDCA2 Protein, CD303 Protein, CLECSF11 Protein, CLECSF7 Protein, DLEC Protein, HECL Protein, PRO34150 Protein, Clec4c Protein, C-type lectin domain family 4 member C Protein, CLEC4C Protein, LOC100733227 Protein
    背景
    Synonyms: DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL,
    Description: CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
    分子量
    26.6 kDa
    NCBI登录号
    NP_569708
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