CLEC4C Protein (AA 48-212) (Fc Tag)
CLEC4C
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
-
- 抗原 See all CLEC4C products
- CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
- 蛋白类型
- Recombinant
- 产品特性
- AA 48-212
-
宿主
- Cynomolgus
-
资源
- HEK-293 Cells
- 标记
- This CLEC4C protein is labelled with Fc Tag.
- 原理
- Cynomolgus BDCA-2 Protein
- 序列
- Tyr48-Ile212
- 产品特性
- Recombinant Cynomolgus BDCA-2 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Tyr48-Ile212.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus BDCA-2, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 13.1ng/ml determined by ELISA. See testing image for detail.
-
C-Type Lectin Domain Family 4, Member C (CLEC4C) (AA 45-213) protein (His-SUMO Tag)
CLEC4C 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- CLEC4C (C-Type Lectin Domain Family 4, Member C (CLEC4C))
- 别名
- BDCA-2 (CLEC4C 产品)
- 别名
- BDCA2 Protein, CD303 Protein, CLECSF11 Protein, CLECSF7 Protein, DLEC Protein, HECL Protein, PRO34150 Protein, Clec4c Protein, C-type lectin domain family 4 member C Protein, CLEC4C Protein, LOC100733227 Protein
- 背景
- BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C after mAb labeling.
- 分子量
- 44.99 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5UWP4
-
You are here:
