HBEGF Protein (Fc Tag)
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- 抗原 See all HBEGF 蛋白
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This HBEGF protein is labelled with Fc Tag.
- 原理
- Recombinant mouse HBEGF (24-160) protein with C-terminal human Fc tag
- 特异性
- Mouse HBEGF (24-160) (Gln24-Thr160) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product HBEGF 蛋白
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Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (His tag)
HBEGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-160) protein (His tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-160) protein (His tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-208) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-208) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) (Active) protein (His tag)HBEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- 别名
- HBEGF (HBEGF 产品)
- 别名
- hbegf Protein, zgc:165443 Protein, HBEGF Protein, zgc:175091 Protein, DTR Protein, DTS Protein, DTSF Protein, HEGFL Protein, Dtr Protein, GFHB Protein, Hb-egf Protein, Hegfl Protein, AW047313 Protein, Dts Protein, HB-EGF Protein, heparin-binding EGF-like growth factor b Protein, heparin binding EGF like growth factor Protein, Heparin-binding EGF-like growth factor Protein, heparin-binding EGF-like growth factor a Protein, heparin-binding EGF-like growth factor Protein, hbegfb Protein, HBEGF Protein, hbegf Protein, hbegfa Protein, Hbegf Protein
- 背景
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Synonymes: AW047313, Dtr, Dts, Hegfl
Description: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function] - 分子量
- predicted molecular mass of 41.3 kDa after removal of the signal peptide.The apparent molecular mass of mHBEGF(24-160)-hFc is 40-55 kDa due to glycosylation.
- UniProt
- Q06186
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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