HBEGF Protein (His tag)
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- 抗原 See all HBEGF 蛋白
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This HBEGF protein is labelled with His tag.
- 原理
- Recombinant Human HBEGF Protein (His Tag)
- 序列
- Leu20-Leu148
- 产品特性
- Recombinant Human Heparin Binding EGF like Growth Factor is produced by our Mammalian expression system and the target gene encoding Leu20-Leu148 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HBEGF 蛋白
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Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (His tag)
HBEGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-160) protein (His tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-160) protein (His tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-208) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-208) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (rho-1D4 tag)Crystallography grade HBEGF 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) (Active) protein (His tag)HBEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
- 别名
- HBEGF (HBEGF 产品)
- 别名
- hbegf Protein, zgc:165443 Protein, HBEGF Protein, zgc:175091 Protein, DTR Protein, DTS Protein, DTSF Protein, HEGFL Protein, Dtr Protein, GFHB Protein, Hb-egf Protein, Hegfl Protein, AW047313 Protein, Dts Protein, HB-EGF Protein, heparin-binding EGF-like growth factor b Protein, heparin binding EGF like growth factor Protein, Heparin-binding EGF-like growth factor Protein, heparin-binding EGF-like growth factor a Protein, heparin-binding EGF-like growth factor Protein, hbegfb Protein, HBEGF Protein, hbegf Protein, hbegfa Protein, Hbegf Protein
- 背景
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Background: Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF) family. It possesses an EGF-like domain, and a heparin-binding motif. Mature HB-EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HB-EGF shows 76 % and 73 % aa sequence identity with rat and mouse HB-EGF, respectively. It is required for normal cardiac valve formation and normal heart function, promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation, it is mitogenic for fibroblasts, but not endothelial cells. HB-EGF classified as a group 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors. Activity associated with ErbB4 binding appears to be limited to non-mitogenic actions, while EGFR binding induces both mitogenic and non-mitogenic activity.
Synonym: Diphtheria toxin receptor, DTR,HEGFL, heparin-binding EGF-like growth factor, DTS, DTSF, heparin-binding epidermal growth factor, proheparin-binding EGF-like growth factor, HB-EGF, pro HB-EGF
- 分子量
- 15.1 kDa
- UniProt
- Q99075
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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