This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
应用范围
SDS-PAGE (SDS), ELISA
原理
SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron)
产品特性
SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1(P13L, ERS31-33del, R203K, G204R). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: B.1.1.529; GISAID clade: GR/484A; Nextstrain clade: 21K). Predicted N-terminus: Met 1
SARS-CoV-2 N
宿主: SARS Coronavirus-2 (SARS-CoV-2)
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
限制
仅限研究用
状态
Lyophilized
缓冲液
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
注意事项
Please avoid repeated freeze-thaw cycles.
储存条件
-20 °C/-80 °C
储存方法
For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at: 4-8°C for 12 months in lyophilized state, -70°C for 3 months under sterile conditions after reconstitution.
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.