NOTCH2 Protein (AA 26-530) (Fc Tag)
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- 抗原 See all NOTCH2 蛋白
- NOTCH2 (Notch 2 (NOTCH2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 26-530
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NOTCH2 protein is labelled with Fc Tag.
- 产品特性
- Human NOTCH2 Protein, Fc Tag (MALS verified)
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product NOTCH2 蛋白
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Notch 2 (NOTCH2) protein (His-Avi Tag,Biotin)
NOTCH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Notch 2 (NOTCH2) (AA 27-136) protein (GST tag)NOTCH2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Notch 2 (NOTCH2) protein (His tag)NOTCH2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Notch 2 (NOTCH2) (AA 1699-2471) protein (His tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1699-2470) protein (His tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- NOTCH2 (Notch 2 (NOTCH2))
- 别名
- NOTCH2 (NOTCH2 产品)
- 别名
- AGS2 Protein, HJCYS Protein, hN2 Protein, AI853703 Protein, N2 Protein, notch6 Protein, sb:cb884 Protein, neurogenic locus notch homolog protein 2 Protein, notch 2 Protein, notch 3 Protein, LOC581186 Protein, NOTCH2 Protein, notch3 Protein, Notch2 Protein, notch2 Protein
- 背景
- Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus . Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation . Positively regulates self-renewal of liver cancer cells .
- 分子量
- 80.5 kDa
- 途径
- Notch Signaling, Stem Cell Maintenance
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