NOTCH2 Protein (AA 26-494, Extracellular Domain) (Fc Tag)
(1 reference)-
- 抗原 See all NOTCH2 蛋白
- NOTCH2 (Notch 2 (NOTCH2))
- 蛋白类型
- Recombinant
- 产品特性
- Extracellular Domain, AA 26-494
-
宿主
- 小鼠
-
资源
- CHO Cells
- 标记
- This NOTCH2 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to mouse DLL1 and DLL4.
- 交叉反应
- 小鼠
- 产品特性
- The extracellular domain of mouse Notch2 (aa 26-494) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product NOTCH2 蛋白
-
Notch 2 (NOTCH2) protein (His-Avi Tag,Biotin)
NOTCH2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Notch 2 (NOTCH2) (AA 26-530) (Active) protein (Fc Tag)NOTCH2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 2 (NOTCH2) (AA 27-136) protein (GST tag)NOTCH2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Notch 2 (NOTCH2) protein (His tag)NOTCH2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Notch 2 (NOTCH2) (AA 1699-2471) protein (His tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1699-2470) protein (His tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2471) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1666-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Notch 2 (NOTCH2) (AA 1697-2470) protein (rho-1D4 tag)Crystallography grade NOTCH2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 50 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
-
-
: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).
-
: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).
-
- 抗原
- NOTCH2 (Notch 2 (NOTCH2))
- 别名
- Notch2 (NOTCH2 产品)
- 别名
- AGS2 Protein, HJCYS Protein, hN2 Protein, AI853703 Protein, N2 Protein, notch6 Protein, sb:cb884 Protein, neurogenic locus notch homolog protein 2 Protein, notch 2 Protein, notch 3 Protein, LOC581186 Protein, NOTCH2 Protein, notch3 Protein, Notch2 Protein, notch2 Protein
- 背景
- Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
- 分子量
- ~87kDa (SDS-PAGE)
- UniProt
- O35516
- 途径
- Notch Signaling, Stem Cell Maintenance
-
