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CD8 alpha Protein (AA 22-182) (His tag)

CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN7013444
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 蛋白
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 22-182
    宿主
    • 15
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    资源
    • 14
    • 7
    • 5
    • 5
    • 3
    HEK-293 Cells
    标记
    This CD8 alpha protein is labelled with His tag.
    产品特性
    Human CD8 alpha / CD8A Protein, His Tag
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD8A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8 alpha (CD8A 产品)
    别名
    cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
    背景
    Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
    分子量
    19.5 kDa
    NCBI登录号
    NP_001759
    途径
    TCR Signaling
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