CD8 alpha Protein (AA 22-182) (His tag,AVI tag,Biotin)
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- 抗原 See all CD8 alpha (CD8A) 蛋白
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 22-182
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD8 alpha protein is labelled with His tag,AVI tag,Biotin.
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 产品特性
- Biotinylated Human CD8 alpha / CD8A Protein, His,Avitag™
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product CD8A 蛋白
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CD8a Molecule (CD8A) (AA 28-196) protein (His tag)
CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD8a Molecule (CD8A) (AA 22-182) protein (His-Avi Tag,Biotin)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) protein (His-IF2DI Tag)CD8A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
CD8a Molecule (CD8A) (AA 22-131) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (AA 1-235) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (Active) protein (His tag)CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD8a Molecule (CD8A) protein (Fc Tag)CD8A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
CD8a Molecule (CD8A) (AA 22-182) protein (His tag)Crystallography grade CD8A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
CD8a Molecule (CD8A) (AA 28-196) protein (His tag)Crystallography grade CD8A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- 别名
- CD8 alpha (CD8A 产品)
- 别名
- cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
- 背景
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
- 分子量
- 21.2 kDa
- NCBI登录号
- NP_001759
- 途径
- TCR Signaling
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