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SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag)

This Recombinant SARS-CoV-2 Spike S1 protein is expressed in HEK-293 Cells.
产品编号 ABIN6992361
发货至: 中国

Quick Overview for SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag) (ABIN6992361)

抗原

See all SARS-CoV-2 Spike S1 蛋白
SARS-CoV-2 Spike S1

蛋白类型

Recombinant

生物活性

Active

宿主

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SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma

资源

  • 95
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HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.
  • 产品特性

    P.1 - gamma

    标记

    This SARS-CoV-2 Spike S1 protein is labelled with His tag.

    原理

    SARS-CoV-2 S1 protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y), His Tag

    序列

    AA 16-685

    产品特性

    SARS-CoV-2 S1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y mutations were identified in the SARS-CoV-2 variant (known as P.1 lineage) which emerged in Brazil.

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C
  • 抗原

    SARS-CoV-2 Spike S1

    别名

    SARS-CoV-2 S1 protein

    物质类

    Viral Protein

    背景

    It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

    分子量

    76.9 kDa
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