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NOTCH3 Protein (AA 40-467) (Fc Tag)

NOTCH3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN6992329
发货至: 中国
  • 抗原 See all NOTCH3 蛋白
    NOTCH3 (Notch 3 (NOTCH3))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 40-467
    宿主
    • 12
    • 5
    资源
    • 8
    • 5
    • 3
    • 1
    HEK-293 Cells
    标记
    This NOTCH3 protein is labelled with Fc Tag.
    原理
    Human NOTCH3 Protein, Fc Tag
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NOTCH3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    储存条件
    -20 °C
  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    NOTCH3 (NOTCH3 产品)
    别名
    CADASIL Protein, CASIL Protein, IMF2 Protein, AW229011 Protein, N3 Protein, hpbk Protein, fa14b08 Protein, notch5 Protein, wu:fa14b08 Protein, notch 3 Protein, NOTCH3 Protein, Notch3 Protein, notch3 Protein
    背景
    Notch3 is one of four mammalian Notch proteins, which act as signalling receptors and involve in developmental patterning, cell fate decisions, regulation of cell survival and proliferation. Notch3 could interact with membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Via ligand activation, notch intracellular domain (NICD) is released and forms a transcriptional activator RBPJ/RBPSUH complex, which activates genes of the enhancer of split locus. Consequently, the activation of Notch3 can lead to the implementation of differentiation, proliferation and apoptotic programs
    分子量
    71.4 kDa
    NCBI登录号
    NP_000426
    途径
    Notch Signaling
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