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TGFB2 Protein (Fc Tag)

TGFB2 宿主: 人 宿主: HEK-293 Cells Recombinant
产品编号 ABIN6964328
发货至: 中国
  • 抗原 See all TGFB2 蛋白
    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
    蛋白类型
    Recombinant
    宿主
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    资源
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    HEK-293 Cells
    标记
    This TGFB2 protein is labelled with Fc Tag.
    序列
    TGFB2 (Ala303-Ser414)+hFc (Glu99-Ala330)
    产品特性
    Tagged Protein: C-Human Fc tag
    纯化方法
    affinity purification
    Top Product
    Discover our top product TGFB2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -80 °C
    储存方法
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    有效期
    12 months
  • 抗原
    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))
    别名
    TGFB2 (TGFB2 产品)
    别名
    LDS4 Protein, TGF-beta2 Protein, tgf-beta2 Protein, tgfb2-A Protein, BB105277 Protein, Tgf-beta2 Protein, Tgfb-2 Protein, TGF-beta 2 Protein, Tgfbr2T Protein, TGFB2 Protein, TGFbeta2 Protein, MGF Protein, TGF-B2 Protein, transforming growth factor beta 2 Protein, transforming growth factor beta 2 L homeolog Protein, transforming growth factor, beta 2 Protein, transforming growth factor, beta receptor 2 Protein, TGFB2 Protein, tgfb2.L Protein, Tgfb2 Protein, Tgfbr2 Protein, tgfb2 Protein
    背景
    Synonymes: G-TSF, LDS4, TGF-beta2
    Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
    分子量
    37.84 kDa
    UniProt
    P61812
    途径
    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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