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TGFB2 Protein (AA 303-414)

This Recombinant TGFB2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7320669
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TGFB2 Protein (AA 303-414) (ABIN7320669)

抗原

See all TGFB2 蛋白
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

蛋白类型

Recombinant

生物活性

Active

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资源

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HEK-293 Cells

应用范围

ELISA

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 303-414

    原理

    Recombinant Mouse TGFB2 Protein

    序列

    Ala303-Ser414

    产品特性

    Recombinant Mouse Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Immobilized Mouse TGFB2 at 10μg/ml(100 μl/well) can bind Human TGFBR2-FC(PKSH033426). The ED50 of Mouse TGFB2 is 0.136μg/mL.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    别名

    TGFB2

    背景

    BSC-1 cell growth inhibitor,Cetermin,G-TSF,Glioblastoma-derived T-cell suppressor factor,MGC116892,Polyergin,TGF-beta-2,TGF-beta2,TGFB2,transforming growth factor beta-2,Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

    分子量

    Calculated MW: 12.7 kDa

    Observed MW: 12 kDa

    UniProt

    P27090

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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