PRAME Protein (Fc Tag)
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- 抗原 See all PRAME 蛋白
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PRAME protein is labelled with Fc Tag.
- 序列
- PRAME (Met1-Asn509)+hFc (Glu99-Ala330)
- 产品特性
- Tagged Protein: C-Human Fc tag
- 纯化方法
- affinity purification
- Top Product
- Discover our top product PRAME 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- 有效期
- 12 months
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- 抗原
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- 别名
- PRAME (PRAME 产品)
- 别名
- PRAME Protein, CT130 Protein, MAPE Protein, OIP-4 Protein, OIP4 Protein, 4930534P07Rik Protein, preferentially expressed antigen in melanoma Protein, PRAME Protein, Prame Protein
- 背景
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Synonymes: CT130, MAPE, OIP-4, OIP4
Description: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] - 分子量
- 81.51 kDa
- UniProt
- P78395
- 途径
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
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