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PRAME 产品

(Preferentially Expressed Antigen in Melanoma (PRAME))

Categories

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

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Featured PRAME Categories

PRAME 抗体

High quality antibodies with extensive validation data.

PRAME ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PRAME 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRAME 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7437779
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN721555
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN949123
Quantity 100 μL
Datasheet Datasheet

Recommended PRAME ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969472
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958702
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN454378
Quantity 96 tests
Datasheet Datasheet

Recommended PRAME 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316123
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124547
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3086568
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PRAME Products

Liu, Zhao, Lu, Ning, Ma, Diaz, OConnor: "A novel testis-specific protein, PRAMEY, is involved in spermatogenesis in cattle." in: Reproduction (Cambridge, England), Vol. 153, Issue 6, pp. 847-863, (2017) (PubMed).

Luetkens, Kobold, Cao, Ristic, Schilling, Tams, Bartels, Templin, Bartels, Hildebrandt, Yousef, Marx, Haag, Bokemeyer, Kröger, Atanackovic: "Functional autoantibodies against SSX-2 and NY-ESO-1 in multiple myeloma patients after allogeneic stem cell transplantation." in: Cancer immunology, immunotherapy : CII, Vol. 63, Issue 11, pp. 1151-62, (2014) (PubMed).

Nalini, Segu, Deepa, Khetan, Vasudevan, Krishnakumar: "Molecular Insights on Post-chemotherapy Retinoblastoma by Microarray Gene Expression Analysis." in: Bioinformatics and biology insights, Vol. 7, pp. 289-306, (2013) (PubMed).

Sakakura, Kubo, Ako, Ikeda, Funayama, Hirahara, Sugawara, Yasu, Kawakami, Momomura: "Determinants of in-hospital death and rupture in patients with a Stanford B aortic dissection." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 71, Issue 10, pp. 1521-4, (2007) (PubMed).

Steinbach, Hermann, Viehmann, Zintl, Gruhn: "Clinical implications of PRAME gene expression in childhood acute myeloid leukemia." in: Cancer genetics and cytogenetics, Vol. 133, Issue 2, pp. 118-23, (2002) (PubMed).

Synonyms and alternative names related to PRAME

preferentially expressed antigen in melanoma (PRAME), preferentially expressed antigen in melanoma (Prame), 4930534P07Rik, CT130, MAPE, OIP-4, OIP4, PRAME

Protein level used designations for PRAME

  • preferentially expressed antigen in melanoma
  • Opa-interacting protein OIP4
  • cancer/testis antigen 130
  • melanoma antigen preferentially expressed in tumors
  • opa-interacting protein 4
  • preferentially expressed antigen of melanoma
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