IL4 Receptor Protein (Fc Tag)
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- 抗原 See all IL4 Receptor (IL4R) 蛋白
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL4 Receptor protein is labelled with Fc Tag.
- 原理
- Recombinant human IL4RA Protein with C-terminal Human Fc tag
- 特异性
- IL4RA (Met26-His232) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL4R 蛋白
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Interleukin 4 Receptor (IL4R) (AA 24-232) protein (Fc Tag)
IL4R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 Receptor (IL4R) (AA 26-232) protein (His tag)IL4R 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 Receptor (IL4R) (AA 24-232) protein (His tag)IL4R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 4 Receptor (IL4R) (AA 26-232) (Active) protein (Fc Tag)IL4R 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 4 Receptor (IL4R) protein (His tag)IL4R 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 4 Receptor (IL4R) protein (Fc Tag)IL4R 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Interleukin 4 Receptor (IL4R) (Active) protein (His tag)IL4R 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Interleukin 4 Receptor (IL4R) (AA 26-135) protein (GST tag)IL4R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 4 Receptor (IL4R) (Active) protein (His tag)IL4R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 4 Receptor (IL4R) (Active) protein (Fc Tag)IL4R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 别名
- IL4RA (IL4R 产品)
- 别名
- IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
- 背景
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Synonymes: CD124, IL-4RA, IL4RA
Description: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. - 分子量
- predicted molecular mass of 49.9 kDa after removal of the signal peptide.The apparent molecular mass of IL4RA-hFc is 55-70 kDa due to glycosylation.
- UniProt
- P24394
- 途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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