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IL4 Receptor Protein (AA 24-232) (Fc Tag)

IL4R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274993
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 蛋白
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    蛋白类型
    Recombinant
    产品特性
    AA 24-232
    宿主
    • 22
    • 11
    • 7
    • 5
    • 4
    • 1
    资源
    • 22
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This IL4 Receptor protein is labelled with Fc Tag.
    原理
    Human IL-4 R alpha/CD124 Protein
    序列
    Gly24-His232
    产品特性
    Recombinant Human IL-4 R alpha/CD124 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly24-His232.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-4, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL-4 R alpha (IL4R 产品)
    别名
    IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
    背景
    Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
    分子量
    50.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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