KIT Protein (His tag)
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- 抗原 See all KIT 蛋白
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KIT protein is labelled with His tag.
- 原理
- Recombinant human CD117 protein with C-terminal 6xHis tag
- 特异性
- CD117 (Gln26-Thr520) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- affinity purification
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Mast/stem Cell Growth Factor Receptor (KIT) (Val560Gly-Mutant) (Active) protein (GST tag)
KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Thr670Ile-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 544-976) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Asp816Tyr-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Asp816Val-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Thr670Ile-Mutant) (Active) protein (His-GST)KIT 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 544-976) (Active) protein (His-GST)KIT 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 26-516) (Active) protein (Fc Tag)KIT 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 1-976) protein (GST tag)KIT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mast/stem Cell Growth Factor Receptor (KIT) (AA 41-140) protein (GST tag)KIT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with deionized water
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 别名
- CD117 (KIT 产品)
- 别名
- C-Kit Protein, CD117 Protein, PBT Protein, SCFR Protein, Bs Protein, Fdc Protein, Gsfsco1 Protein, Gsfsco5 Protein, Gsfsow3 Protein, SCO1 Protein, SCO5 Protein, SOW3 Protein, Ssm Protein, Tr-kit Protein, W Protein, c-KIT Protein, c-kit Protein, MGF Protein, KIT Protein, C-KIT Protein, kit Protein, receptor Protein, sparse Protein, Xkl-1 Protein, kit-a Protein, kit-b Protein, kl1-A Protein, krk1 Protein, pbt Protein, scfr Protein, KIT proto-oncogene receptor tyrosine kinase Protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a Protein, KIT proto-oncogene receptor tyrosine kinase S homeolog Protein, KIT Protein, Kit Protein, kita Protein, kit Protein, kit.S Protein
- 背景
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Synonymes: C-Kit, CD117, MASTC, PBT, SCFR, KIT
Description: This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020] - 分子量
- predicted molecular mass of 56.5 kDa after removal of the signal peptide.The apparent molecular mass of CD117-His is 70-100 kDa due to glycosylation.
- 基因ID
- 3815
- UniProt
- P10721
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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