KIT Protein (AA 26-516) (Fc Tag)
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- 抗原 See all KIT 蛋白
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 26-516
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This KIT protein is labelled with Fc Tag.
- 序列
- AA 26-516
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 81.9 kDa. The protein migrates as 100-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KIT 蛋白
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Mast/stem Cell Growth Factor Receptor (KIT) protein (His tag)
KIT 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Mast/stem Cell Growth Factor Receptor (KIT) (Thr670Ile-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 544-976) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Asp816Tyr-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Asp816Val-Mutant) (Active) protein (GST tag)KIT 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (Thr670Ile-Mutant) (Active) protein (His-GST)KIT 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 544-976) (Active) protein (His-GST)KIT 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Mast/stem Cell Growth Factor Receptor (KIT) (AA 1-976) protein (GST tag)KIT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mast/stem Cell Growth Factor Receptor (KIT) (AA 41-140) protein (GST tag)KIT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 别名
- CD117 (KIT 产品)
- 别名
- C-Kit Protein, CD117 Protein, PBT Protein, SCFR Protein, Bs Protein, Fdc Protein, Gsfsco1 Protein, Gsfsco5 Protein, Gsfsow3 Protein, SCO1 Protein, SCO5 Protein, SOW3 Protein, Ssm Protein, Tr-kit Protein, W Protein, c-KIT Protein, c-kit Protein, MGF Protein, KIT Protein, C-KIT Protein, kit Protein, receptor Protein, sparse Protein, Xkl-1 Protein, kit-a Protein, kit-b Protein, kl1-A Protein, krk1 Protein, pbt Protein, scfr Protein, KIT proto-oncogene receptor tyrosine kinase Protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a Protein, KIT proto-oncogene receptor tyrosine kinase S homeolog Protein, KIT Protein, Kit Protein, kita Protein, kit Protein, kit.S Protein
- 背景
- Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.
- 分子量
- 81.9 kDa
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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