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TNFRSF18 Protein (Fc-His Tag)

TNFRSF18 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6961091
发货至: 中国
  • 抗原 See all TNFRSF18 蛋白
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    蛋白类型
    Recombinant
    宿主
    • 20
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    资源
    • 24
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    HEK-293 Cells
    标记
    This TNFRSF18 protein is labelled with Fc-His Tag.
    原理
    Recombinant human GITR protein with C-terminal human Fc and 6xHis tag
    特异性
    GITR (Gln26-Pro162) hFc (Glu99-Ala330) 6xHis
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product TNFRSF18 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    别名
    GITR (TNFRSF18 产品)
    别名
    GITR Protein, TNFRSF18 Protein, AITR Protein, Gitr Protein, CD357 Protein, GITR-D Protein, TNF receptor superfamily member 18 Protein, tumor necrosis factor receptor superfamily, member 18 Protein, TNFRSF18 Protein, Tnfrsf18 Protein
    背景
    Synonymes: AITR, GITR, TNFRSF18, CD357
    Description: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    分子量
    predicted molecular mass of 51-52 kDa after removal of the signal peptide.
    基因ID
    8784
    UniProt
    Q9Y5U5
    途径
    Cancer Immune Checkpoints
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