BEBOV GP Protein (AA 33-324) (His tag)
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- 抗原 See all BEBOV GP products
- BEBOV GP (Bundibugyo Ebola Virus Envelope Glycoprotein (BEBOV GP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 33-324
- 宿主
- Ebola Virus
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资源
- HEK-293 Cells
- 标记
- This BEBOV GP protein is labelled with His tag.
- 原理
- Recombinant Ebolavirus BDBV(subtype Bundibugyo,strain Uganda 2007) Small/secreted Glycoprotein (sGP) protein produced in HEK293 cells. Protein contains a C-terminal 6x His-tag
- 特异性
- Recombinant Ebolavirus BDBV (subtype Bundibugyo,strain Uganda 2007) Small/secreted Glycoprotein (sGP) produced in HEK293 cells, incorporating a C-terminal 6x His-tag. Greater than 80% purity.
- 产品特性
- Ebola Virus Secreted Glycoprotein (sGP) (Bundibugyo)
- 纯度
- >95 %
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Bundibugyo Ebola Virus Envelope Glycoprotein (BEBOV GP) protein (Fc Tag)
BEBOV GP 宿主: Ebola Virus 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
Bundibugyo Ebola Virus Envelope Glycoprotein (BEBOV GP) protein (His tag)BEBOV GP 宿主: Ebola Virus 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE.
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- 说明
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Ebola virus secreted glycoprotein protein (sGP) is Ile 33 – Arg 324 (Accession # B8XCN1), fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 34.3 kDa. The protein is expressed in HEK293 cells. DTT-reduced Protein migrates as 40-55 kDa in SDS-PAGE.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C
- 储存方法
- 4°C
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- 抗原
- BEBOV GP (Bundibugyo Ebola Virus Envelope Glycoprotein (BEBOV GP))
- 别名
- Ebola Secreted Glycoprotein (sGP) (Bundibugyo) (BEBOV GP 产品)
- 物质类
- Viral Protein
- 背景
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The virulence of EBOV may be partially attributed to the Ebola virus secreted glycoprotein (sGP), which is the main product transcribed from its GP gene. Ebola virus secreted glycoprotein is secreted from infected cells and can be readily detected in the serum of EBOV-infected hosts. Mature sGP is produced from a precursor by proteolytic cleavage by host cell proteases such as furin. sGP monomers bind to each other to form a homodimer.
The role of Ebola virus secreted glycoprotein in EBOV pathogenesis is unclear, but is examined in detail by de la Vega et al (2015) - UniProt
- B8XCN1
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