IL-5 Protein (AA 20-134) (His tag)
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- 抗原 See all IL-5 (IL5) 蛋白
- IL-5 (IL5) (Interleukin 5 (IL5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 20-134
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL-5 protein is labelled with His tag.
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- IL-5 (IL5) (Interleukin 5 (IL5))
- 别名
- IL-5 (IL5 产品)
- 别名
- EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
- 背景
- Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.
- 分子量
- 15.0 kDa
- NCBI登录号
- NP_000870
- 途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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