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IL-5 Protein (AA 21-133) (His-Avi Tag)

IL5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274959
发货至: 中国
  • 抗原 See all IL-5 (IL5) 蛋白
    IL-5 (IL5) (Interleukin 5 (IL5))
    蛋白类型
    Recombinant
    产品特性
    AA 21-133
    宿主
    • 20
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    • 7
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    小鼠
    资源
    • 27
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    HEK-293 Cells
    标记
    This IL-5 protein is labelled with His-Avi Tag.
    原理
    Mouse IL-5 Protein
    序列
    Met21-Gly133
    产品特性
    Recombinant Mouse IL-5 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Met21-Gly133.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.495 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL5 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 7.0).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL-5 (IL5) (Interleukin 5 (IL5))
    别名
    IL-5 (IL5 产品)
    别名
    EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
    背景
    IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the key immune effector cells such as eosinophilic asthma (EA), hypereosinophilic syndrome (HES), eosinophilic esophagitis (EE), and eosinophilic granulomatosis with polyangiitis (EGPA).
    分子量
    16.03 kDa. Due to glycosylation, the protein migrates to 16.03 kDa and 20-32 kDa based on Tris-Bis PAGE result.
    UniProt
    P04401
    途径
    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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