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Insulin Receptor Protein (INSR) (AA 28-944) (His tag)

INSR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6809906
发货至: 中国
  • 抗原 See all Insulin Receptor (INSR) 蛋白
    Insulin Receptor (INSR)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 28-944
    宿主
    • 18
    • 6
    • 3
    • 1
    • 1
    资源
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Insulin Receptor protein is labelled with His tag.
    序列
    AA 28-944
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product INSR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
  • 抗原
    Insulin Receptor (INSR)
    别名
    Insulin R (INSR 产品)
    别名
    CD220 Protein, HHF5 Protein, 4932439J01Rik Protein, D630014A15Rik Protein, IR Protein, IR-A Protein, IR-B Protein, 18402 Protein, CG18402 Protein, DIHR Protein, DILR Protein, DIR Protein, DIRH Protein, DIRbeta Protein, DInR Protein, DInr Protein, Dir-a Protein, Dir-b Protein, Dmel\\CG18402 Protein, INR Protein, INS Protein, Inr Protein, Inr-alpha Protein, Inr-beta Protein, InsR Protein, dINR Protein, dIR Protein, dIRH Protein, dInR Protein, dInr Protein, dInsR Protein, dinr Protein, dir Protein, er10 Protein, inr Protein, insulin/insulin-like growth factor receptor Protein, l(3)05545 Protein, l(3)93Dj Protein, l(3)er10 Protein, lnR Protein, ir-A Protein, CTK-1 Protein, ir Protein, INSR Protein, NV14476 Protein, cd220 Protein, hhf5 Protein, insulin receptor Protein, Insulin-like receptor Protein, insulin receptor L homeolog Protein, INSR Protein, Insr Protein, InR Protein, LOC100122567 Protein, LOC100451802 Protein, insr.L Protein
    背景
    Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulin-binding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulin-like growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1.
    分子量
    106.5 kDa
    NCBI登录号
    NP_000199
    途径
    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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