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CDK2 Protein (AA 1-298) (His tag)

CDK2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667950
发货至: 中国
  • 抗原 See all CDK2 蛋白
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-298
    宿主
    • 12
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CDK2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    CDK2, 1-298aa, Human, His tag, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CDK2 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
    储存条件
    4 °C
  • 抗原
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    别名
    CDK2 (CDK2 产品)
    别名
    p33(CDK2) Protein, A630093N05Rik Protein, wu:fa10c02 Protein, zgc:56598 Protein, zgc:77684 Protein, eg1 Protein, CDKN2 Protein, cdk2L Protein, cyclin dependent kinase 2 Protein, cyclin-dependent kinase 2 Protein, cyclin-dependent kinase 2 S homeolog Protein, CDK2 Protein, Cdk2 Protein, cdk2 Protein, cdk2.S Protein
    背景
    CDK2, also known as cyclin-depentent kinase 2, is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Cyclin-depentent kinase 2, p33, CDK2. NCBI no.: NP_001789
    分子量
    35.0 kDa (306aa), confirmed by MALDI-TOF
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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