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Aminoacylase 1 Protein (ACY1) (AA 1-408) (His tag)

ACY1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN667808
发货至: 中国
  • 抗原 See all Aminoacylase 1 (ACY1) 蛋白
    Aminoacylase 1 (ACY1)
    蛋白类型
    Recombinant
    产品特性
    AA 1-408
    宿主
    • 6
    • 3
    • 1
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Aminoacylase 1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    ACY1, 1-408aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ACY1 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
    储存条件
    4 °C
  • 抗原
    Aminoacylase 1 (ACY1)
    别名
    ACY1 (ACY1 产品)
    别名
    si:zfos-226g1.1 Protein, zgc:55605 Protein, zgc:76955 Protein, acy1 Protein, acy1d Protein, acylase Protein, ACY1 Protein, ACY-1 Protein, ACY1D Protein, 1110014J22Rik Protein, Acy-1 Protein, Acy1a Protein, Acy1b Protein, aminoacylase 1 Protein, aminoacylase 1, gene 1 S homeolog Protein, aminoacylase 1, gene 1 Protein, ACY1 Protein, acy1 Protein, acy1.1.S Protein, acy1.1 Protein, Acy1 Protein
    背景
    Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids. Recombinant human ACY1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ACY1D, ACYLASE, Aminoacylase 1. NCBI no.: NP_000657
    分子量
    48.0kDa (428aa) confirmed by MALDI-TOF
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