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TICAM2 Protein (AA 1-235) (His tag)

TICAM2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN667668
发货至: 中国
  • 抗原 See all TICAM2 蛋白
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-235
    宿主
    • 6
    • 3
    • 1
    • 1
    资源
    • 6
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TICAM2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    TICAM2, 1-235aa, Human, His tag, E.coli
    纯度
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TICAM2 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
    储存条件
    4 °C
  • 抗原
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    别名
    TICAM2 (TICAM2 产品)
    别名
    MyD88-4 Protein, TICAM-2 Protein, TIRAP3 Protein, TIRP Protein, TRAM Protein, B430113A10 Protein, Tirp Protein, Trif Protein, toll like receptor adaptor molecule 2 Protein, toll-like receptor adaptor molecule 2 Protein, TICAM2 Protein, Ticam2 Protein
    背景
    Toll TIR domain-containing adapter molecule 2, also known as TICAM2, is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. It is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Recombinant human TICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TIR domain-containing adapter molecule 2, TICAM-2, TIRAP3, TIRP, TRAM. NCBI no.: NP_067681
    分子量
    29.4 kDa (259aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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