TICAM2 Protein (AA 1-235) (His tag)
-
- 抗原 See all TICAM2 蛋白
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-235
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This TICAM2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- TICAM2, 1-235aa, Human, His tag, E.coli
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TICAM2 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
- 储存条件
- 4 °C
-
- 抗原
- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
- 别名
- TICAM2 (TICAM2 产品)
- 别名
- MyD88-4 Protein, TICAM-2 Protein, TIRAP3 Protein, TIRP Protein, TRAM Protein, B430113A10 Protein, Tirp Protein, Trif Protein, toll like receptor adaptor molecule 2 Protein, toll-like receptor adaptor molecule 2 Protein, TICAM2 Protein, Ticam2 Protein
- 背景
- Toll TIR domain-containing adapter molecule 2, also known as TICAM2, is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. It is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Recombinant human TICAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TIR domain-containing adapter molecule 2, TICAM-2, TIRAP3, TIRP, TRAM. NCBI no.: NP_067681
- 分子量
- 29.4 kDa (259aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-