Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag)
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- 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 蛋白
- Dual Specificity Phosphatase 3 (DUSP3)
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-185
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- His tag
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- DUSP3, 1-185 aa , Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DUSP3 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford)
- 缓冲液
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
- 储存条件
- 4 °C
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- 抗原
- Dual Specificity Phosphatase 3 (DUSP3)
- 别名
- DUSP3 (DUSP3 产品)
- 别名
- dusp3 Protein, si:bz18k17.3 Protein, si:rp71-18k17.3 Protein, VHR Protein, RGD1560049 Protein, 2210015O03Rik Protein, 5031436O03Rik Protein, T-DSP11 Protein, dual specificity phosphatase 3 Protein, dual specificity phosphatase 3b Protein, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Protein, DUSP3 Protein, dusp3b Protein, Dusp3 Protein
- 物质类
- Viral Protein
- 背景
- DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues. DUSP3 Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. Recombinant human DUSP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Dual specificity protein phosphatase 3, VHR. NCBI no.: NP_004081
- 分子量
- 22.6 kDa (205aa), confirmed by MALDI-TOF
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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