Dual Specificity Phosphatase 3 蛋白
(Dual Specificity Phosphatase 3 (DUSP3))
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag) | 人 | HEK-293 Cells |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag) | 小鼠 | HEK-293 Cells |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-205) protein (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) (Active) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (GST tag) | 人 | 小麦胚 |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-144) protein (GST tag) | 人 | 小麦胚 |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 31-185) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| Dual Specificity Phosphatase 3 (DUSP3) (Active) 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) (Active) 蛋白 | 人 | Baculovirus infected Insect Cells |
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| Dual Specificity Phosphatase 3 (DUSP3) protein (His-GST) | 人 | Baculovirus infected Insect Cells |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| Dual Specificity Phosphatase 3 (DUSP3) (AA 2-185) protein (His tag) | 人 | Bacteria |
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| Dual Specificity Phosphatase 3 (DUSP3) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| Dual Specificity Phosphatase 3 (DUSP3) protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- EAA (Enzyme Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % pure
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- 宿主
- 人
- 宿主
- Bacteria
- 蛋白类型
- Recombinant
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Aliases for Dual Specificity Phosphatase 3 蛋白
dual specificity phosphatase 3 (DUSP3) 蛋白dual specificity phosphatase 3b (dusp3b) 蛋白
dual specificity phosphatase 3 (Dusp3) 蛋白
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3) 蛋白
2210015O03Rik 蛋白
5031436O03Rik 蛋白
dusp3 蛋白
RGD1560049 蛋白
si:bz18k17.3 蛋白
si:rp71-18k17.3 蛋白
T-DSP11 蛋白
VHR 蛋白
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