DUSP12 蛋白
(Dual Specificity Phosphatase 12 (DUSP12))
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].
Recommended next Filters:
6 results
custom-made
DUSP12
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
DUSP12
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for DUSP12 蛋白
dual specificity phosphatase 12 (DUSP12) 蛋白dual specificity phosphatase 12 (dusp12) 蛋白
dual specificity phosphatase 12 L homeolog (dusp12.L) 蛋白
Dual specificity protein phosphatase 12 (GL50803_36315) 蛋白
dual specificity protein phosphatase 12 (MGYG_01770) 蛋白
dual specificity phosphatase 12 (Dusp12) 蛋白
1190004O14Rik 蛋白
AA027408 蛋白
AW049275 蛋白
DUSP1 蛋白
DUSP12 蛋白
dusp12 蛋白
ESTM36 蛋白
GKAP 蛋白
LMW-DSP4 蛋白
MGC154526 蛋白
mVH1 蛋白
T-DSP4 蛋白
VH1 蛋白
YVH1 蛋白
zgc:114069 蛋白
您还需要查找其他产品吗？
You are here:
