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DUSP12 Protein (Myc-DYKDDDDK Tag)

DUSP12 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2719827
发货至: 中国
  • 抗原 See all DUSP12 蛋白
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This DUSP12 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human DUSP12 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DUSP12 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    别名
    Dusp12 (DUSP12 产品)
    别名
    DUSP12 Protein, dusp12 Protein, zgc:114069 Protein, MGC154526 Protein, DUSP1 Protein, YVH1 Protein, 1190004O14Rik Protein, AA027408 Protein, AW049275 Protein, ESTM36 Protein, LMW-DSP4 Protein, T-DSP4 Protein, VH1 Protein, mVH1 Protein, GKAP Protein, dual specificity phosphatase 12 Protein, dual specificity phosphatase 12 L homeolog Protein, Dual specificity protein phosphatase 12 Protein, dual specificity protein phosphatase 12 Protein, DUSP12 Protein, dusp12 Protein, dusp12.L Protein, GL50803_36315 Protein, MGYG_01770 Protein, Dusp12 Protein
    背景
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
    分子量
    37.5 kDa
    NCBI登录号
    NP_009171
    途径
    Regulation of Carbohydrate Metabolic Process
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