Dual Specificity Phosphatase 3 (DUSP3) protein (His-GST)
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) protein (His-GST) (ABIN7318028)
抗原
See all Dual Specificity Phosphatase 3 (DUSP3) 蛋白蛋白类型
宿主
资源
纯度
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标记
- His-GST
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原理
- Recombinant Human DUSP3/VHR Protein (His & GST Tag)
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序列
- Met 1-Pro 185
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产品特性
- A DNA sequence encoding the human VHR (P51452) (Met 1-Pro 185) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag)
custom-made DUSP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (His tag)custom-made DUSP3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (GST tag)DUSP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-144) protein (GST tag)DUSP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-205) protein (His-IF2DI Tag)DUSP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) (Active) protein (His tag)DUSP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, EAA Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 2 mM GSH
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Dual Specificity Phosphatase 3 (DUSP3)
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别名
- DUSP3/VHR
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物质类
- Viral Protein
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背景
- DUSP3,Dual specificity protein phosphatase 3,Dual specificity protein phosphatase VHR,VHR,Vaccinia H1-related phosphatase,Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. Unlike typical DUSPs, VHR lacks mitogen-activated protein kinase (MAPK)-binding domain, and shows poor activity against MAPKs. VHR often act on bisphosphorylated protein substrates, it displays a strong preference for dephosphorylating phosphotyrosine residues over phosphothreonine residues. VHR has been identified as a novel regulator of extracellular regulated kinases (ERKs). VHR is responsible for the rapid inactivation of ERK following stimulation and for its repression in quiescent cells. VHR is a negative regulator of the Erk and Jnk pathways in T cells and, therefore, may play a role in aspects of T lymphocyte physiology that depend on these kinases.
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分子量
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Calculated MW: 48.3 kDa
Observed MW: 44 kDa
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基因ID
- 1845
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UniProt
- P51452
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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