Dual Specificity Phosphatase 3 (DUSP3) protein (His tag)
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- 抗原 See all Dual Specificity Phosphatase 3 (DUSP3) 蛋白
- Dual Specificity Phosphatase 3 (DUSP3)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- His tag
- 原理
- Recombinant Human DUSP3/VHR Protein (His Tag)
- 序列
- Ser2-Pro185
- 产品特性
- Recombinant Human DUSP3 is produced by our E.coli expression system and the target gene encoding Ser2-Pro185 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- Discover our top product DUSP3 蛋白
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Dual Specificity Phosphatase 3 (DUSP3) (AA 1-205) protein (His tag)
DUSP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-144) protein (GST tag)DUSP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (GST tag)DUSP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 76-185) protein (GST tag)DUSP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag)Crystallography grade DUSP3 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) protein (Strep Tag)Crystallography grade DUSP3 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Dual Specificity Phosphatase 3 (DUSP3) protein (Myc-DYKDDDDK Tag)DUSP3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Dual Specificity Phosphatase 3 (DUSP3)
- 别名
- DUSP3/VHR (DUSP3 产品)
- 别名
- dusp3 Protein, si:bz18k17.3 Protein, si:rp71-18k17.3 Protein, VHR Protein, RGD1560049 Protein, 2210015O03Rik Protein, 5031436O03Rik Protein, T-DSP11 Protein, dual specificity phosphatase 3 Protein, dual specificity phosphatase 3b Protein, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Protein, DUSP3 Protein, dusp3b Protein, Dusp3 Protein
- 物质类
- Viral Protein
- 背景
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Background: Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs are major modulators of critical signalling pathways that are dysregulated in various diseases. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in human tissues including breast and ovarian.DUSP3 shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Human DUSP3 specifically dephosphorylates and inactivates ERK1 and ERK2.
Synonym: Dual specificity protein phosphatase 3,DUSP3,Dual specificity protein phosphatase VHR,Vaccinia H1-related phosphatase,VHR
- 分子量
- 22.6 kDa
- UniProt
- P51452
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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