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Deoxyuridine Triphosphatase (DUT) (AA 70-252) protein (His tag)

DUT 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS – PAGE SDS
产品编号 ABIN667220
发货至: 中国
  • 抗原 See all Deoxyuridine Triphosphatase (DUT) 蛋白
    Deoxyuridine Triphosphatase (DUT)
    蛋白类型
    Recombinant
    产品特性
    AA 70-252
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    资源
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    大肠杆菌(E. Coli)
    标记
    His tag
    应用范围
    SDS-PAGE (SDS)
    产品特性
    DUT, 70-252aa, Human, His tag, E.coli
    纯度
    > 90 % by SDS – PAGE
    Top Product
    Discover our top product DUT 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
    储存条件
    4 °C
  • 抗原
    Deoxyuridine Triphosphatase (DUT)
    别名
    DUT (DUT 产品)
    别名
    BcDNA:LD08534 Protein, CG4584 Protein, Dmel\\CG4584 Protein, LD08534 Protein, UTPase Protein, anon-SAGE:Wang-077 Protein, dUTPase Protein, Tb07.27E10.390 Protein, dutpase Protein, 5031412I06Rik Protein, 5133400F09Rik Protein, D2Bwg0749e Protein, Dutp Protein, PIP4 Protein, deoxyuridine triphosphatase Protein, Deoxyuridine triphosphatase Protein, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 Protein, involved in nucleotide metabolism Protein, tegument protein Protein, dUTPase Protein, deoxyuridine triphosphatase L homeolog Protein, DUT Protein, dUTPase Protein, P18 Protein, AlHV1gp51 Protein, UL50 Protein, HVT058 Protein, ORF9 Protein, ORF8 Protein, U45 Protein, GAMMAHV.ORF54 Protein, Tc00.1047053509151.130 Protein, Tc00.1047053508175.160 Protein, Tb927.7.5160 Protein, dut.L Protein, Dut Protein
    物质类
    Viral Protein
    背景
    DUT, also known as dUTP pyrophosphatase, is a ubiquitous enzyme that functions in nucleotide metabolism. This protein, in the presence of magnesium ions, is responsible for hydrolyzing dUTP to dUMP and diphosphate. This reaction is important for keeping the intracellular dUTP concentration low so that uracil does not become incorporated into DNA. Extensive incorporation of uracil into DNA can ultimately lead to cell death. This suggests that DUT is essential for cell viability, further implying that it is a potential target for anticancer therapy. Recombinant human DUT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: dUTPase, dUTP pyrophosphatase, FLJ20622, dUTPase, dUTP pyrophosphatase, FLJ20622. NCBI no.: NP_001020419
    分子量
    21.6 kDa (204aa), confirmed by MALDI-TOF
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