Deoxyuridine Triphosphatase (DUT) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)
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- 抗原 See all Deoxyuridine Triphosphatase (DUT) 蛋白
- Deoxyuridine Triphosphatase (DUT)
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 3
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- Myc-DYKDDDDK Tag
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human DUT (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DUT 蛋白
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Deoxyuridine Triphosphatase (DUT) (AA 1-164) protein (His tag)
DUT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Deoxyuridine Triphosphatase (DUT) (AA 70-252) protein (His tag)DUT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Deoxyuridine Triphosphatase (DUT) (AA 68-164) protein (GST tag)DUT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 41-122) protein (GST tag)DUT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 1-252) protein (GST tag)DUT 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Deoxyuridine Triphosphatase (DUT) (AA 1-278), (full length) protein (His-SUMO Tag)DUT 宿主: Epstein-Barr Virus (EBV) 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Deoxyuridine Triphosphatase (DUT) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DUT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Deoxyuridine Triphosphatase (DUT)
- 别名
- Dut (DUT 产品)
- 别名
- BcDNA:LD08534 Protein, CG4584 Protein, Dmel\\CG4584 Protein, LD08534 Protein, UTPase Protein, anon-SAGE:Wang-077 Protein, dUTPase Protein, Tb07.27E10.390 Protein, dutpase Protein, 5031412I06Rik Protein, 5133400F09Rik Protein, D2Bwg0749e Protein, Dutp Protein, PIP4 Protein, deoxyuridine triphosphatase Protein, Deoxyuridine triphosphatase Protein, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 Protein, involved in nucleotide metabolism Protein, tegument protein Protein, dUTPase Protein, deoxyuridine triphosphatase L homeolog Protein, DUT Protein, dUTPase Protein, P18 Protein, AlHV1gp51 Protein, UL50 Protein, HVT058 Protein, ORF9 Protein, ORF8 Protein, U45 Protein, GAMMAHV.ORF54 Protein, Tc00.1047053509151.130 Protein, Tc00.1047053508175.160 Protein, Tb927.7.5160 Protein, dut.L Protein, Dut Protein
- 物质类
- Viral Protein
- 背景
- This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
- 分子量
- 15.2 kDa
- NCBI登录号
- NP_001020420
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