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CRADD Protein (AA 1-199) (His tag)

CRADD 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN667087
发货至: 中国
  • 抗原 See all CRADD 蛋白
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    蛋白类型
    Recombinant
    产品特性
    AA 1-199
    宿主
    • 7
    • 1
    资源
    • 5
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CRADD protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    产品特性
    CRADD, 1-199aa, Human,His tagged, Recombinant, E.coli
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product CRADD 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid in 20mM TRIS pH 8.0, 20% glycerol
    储存条件
    4 °C
  • 抗原
    CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
    别名
    CRADD (CRADD 产品)
    别名
    cradd Protein, MGC89035 Protein, zgc:101717 Protein, CRADD Protein, DKFZp468A2219 Protein, LOC100226369 Protein, raidd Protein, MGC78788 Protein, MRT34 Protein, RAIDD Protein, CASP2 and RIPK1 domain containing adaptor with death domain Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 1 Protein, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog Protein, CRADD Protein, cradd.1 Protein, cradd Protein, cradd.2.S Protein, Cradd Protein
    背景
    CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recombinant CRADD protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: RAIDD, CRADD, Caspase and RIP adapter with death domain, Caspase and RIP adapter with death domain CASP2 and RIPK1 domain containing adaptor with death domain, Death adaptor molecule RAIDD, Death domain containing protein CRADD, MGC9163, RIP associated ICH1/CED3 homologous protein with death domain, RIP associated protein with a death domain,. NCBI no.: NP_003796
    分子量
    24.9kDa (219aa), confirmed by MALDI-TOF.
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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