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FH Protein (AA 44-510)

FH 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN666730
发货至: 中国
  • 抗原 See all FH 蛋白
    FH (Fumarate Hydratase (FH))
    蛋白类型
    Recombinant
    产品特性
    AA 44-510
    宿主
    • 7
    • 2
    • 1
    • 1
    • 1
    资源
    • 7
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    SDS-PAGE (SDS)
    产品特性
    Fumarase, 44-510aa, Human, Recombinant, E.coli
    纯度
    > 95 % by SDS - PAGE
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
    储存条件
    4 °C
  • 抗原
    FH (Fumarate Hydratase (FH))
    别名
    Fumarase (FH 产品)
    别名
    FH Protein, DDBDRAFT_0205237 Protein, DDBDRAFT_0231397 Protein, DDBDRAFT_0231400 Protein, DDB_0205237 Protein, DDB_0231397 Protein, DDB_0231400 Protein, HLRCC Protein, LRCC Protein, MCL Protein, MCUL1 Protein, Fh1 Protein, im:7152785 Protein, ns:zf-e152 Protein, zf-e152 Protein, zgc:66253 Protein, zgc:77498 Protein, Fh Protein, Fh-1 Protein, fumarate hydratase Protein, fumarate hydratase 1 Protein, FH Protein, fumH Protein, Fh Protein, fh Protein, Fh1 Protein
    背景
    Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: FH, HLRCC, LRCC, MCL, MCUL1 , Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCUL 1, Multiple hereditary cutaneous leiomyomata. NCBI no.: NP_000134
    分子量
    50.2kDa (467aa), confirmed by MALDI-TOF.
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