IL2 Receptor beta Protein (AA 27-239) (His tag)
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- 抗原 See all IL2 Receptor beta (IL2RB) 蛋白
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-239
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL2 Receptor beta protein is labelled with His tag.
- 序列
- AA 27-239
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.4 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >90 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL2RB 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- 抗原
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- 别名
- IL-2 R beta (IL2RB 产品)
- 别名
- IL2RB Protein, il-2rb Protein, CD122 Protein, IL15RB Protein, P70-75 Protein, IL2RBC Protein, IL-15Rbeta Protein, IL15Rbeta Protein, Il-2/15Rbeta Protein, Il-2Rbeta Protein, p70 Protein, interleukin 2 receptor subunit beta Protein, interleukin-2 receptor subunit beta Protein, interleukin 2 receptor, beta Protein, interleukin 2 receptor, beta chain Protein, IL2RB Protein, LOC510185 Protein, il2rb Protein, Il2rb Protein
- 背景
- Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
- 分子量
- 25.4 kDa
- NCBI登录号
- NP_000869
- 途径
- JAK/STAT Signaling, Growth Factor Binding
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