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IL2 Receptor beta Protein (AA 27-239) (His tag)

IL2RB 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274056
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 蛋白
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    蛋白类型
    Recombinant
    产品特性
    AA 27-239
    宿主
    • 18
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Cynomolgus
    资源
    • 13
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL2 Receptor beta protein is labelled with His tag.
    原理
    Cynomolgus IL-2 R beta/CD122 Protein
    序列
    Ala27-Asp239
    产品特性
    Recombinant Cynomolgus IL-2 R beta/CD122 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Asp239.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.182 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL2RB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    IL-2 R beta (IL2RB 产品)
    别名
    IL2RB Protein, il-2rb Protein, CD122 Protein, IL15RB Protein, P70-75 Protein, IL2RBC Protein, IL-15Rbeta Protein, IL15Rbeta Protein, Il-2/15Rbeta Protein, Il-2Rbeta Protein, p70 Protein, interleukin 2 receptor subunit beta Protein, interleukin-2 receptor subunit beta Protein, interleukin 2 receptor, beta Protein, interleukin 2 receptor, beta chain Protein, IL2RB Protein, LOC510185 Protein, il2rb Protein, Il2rb Protein
    背景
    IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.
    分子量
    25.6 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.
    UniProt
    Q38J85
    途径
    JAK/STAT Signaling, Growth Factor Binding
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