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IL2 Receptor beta Protein (AA 27-239) (Fc Tag)

IL2RB 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2181388
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 蛋白
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 27-239
    宿主
    • 17
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 13
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL2 Receptor beta protein is labelled with Fc Tag.
    序列
    AA 27-239
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL2RB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    IL-2 R beta (IL2RB 产品)
    背景
    Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
    分子量
    50.7 kDa
    NCBI登录号
    NP_000869
    途径
    JAK/STAT Signaling, Growth Factor Binding
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