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nectin-3 Protein (AA 58-404) (His tag)

NECTIN3 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN6388148
发货至: 中国
  • 抗原 See all nectin-3 (NECTIN3) 蛋白
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    蛋白类型
    Recombinant
    产品特性
    AA 58-404
    宿主
    • 18
    • 4
    资源
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    标记
    This nectin-3 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    GPIIVEPHVT AVWGKNVSLK CLIEVNETIT QISWEKIHGK SSQTVAVHHP QYGFSVQGEY QGRVLFKNYS LNDATITLHN IGFSDSGKYI CKAVTFPLGN AQSSTTVTVL VEPTVSLIKG PDSLIDGGNE TVAAICIAAT GKPVAHIDWE GDLGEMESTT TSFPNETATI ISQYKLFPTR FARGRRITCV VKHPALEKDI RYSFILDIQY APEVSVTGYD GNWFVGRKGV NLKCNADANP PPFKSVWSRL DGQWPDGLLA SDNTLHFVHP LTFNYSGVYI CKVTNSLGQR SDQKVIYISD PPTTTTLQPT IQWHPSTADI EDLATEPKKL PFPLSTLATI KDDTIATLEH HHHHH
    纯度
    > 90 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product NECTIN3 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 20 % glycerol, 1  mM DTT.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
    别名
    NECTIN3 (NECTIN3 产品)
    别名
    PVRL3 Protein, CD113 Protein, CDW113 Protein, NECTIN-3 Protein, PPR3 Protein, PRR3 Protein, PVRR3 Protein, 2610301B19Rik Protein, 3000002N23Rik Protein, 4921513D19Rik Protein, AA407785 Protein, AU016832 Protein, AW538082 Protein, nectin cell adhesion molecule 3 Protein, poliovirus receptor-related 3 Protein, Nectin3 Protein, NECTIN3 Protein, PVRL3 Protein, nectin3 Protein
    背景
    NECTIN3, also known as nectin-3 isoform 1, is a member of the nectin family. It is proposed to initiate cell-cell adhesion to promote cell attachment and to allow subsequent formation of JAM- and cadherin-based intercellular junctions. It has been shown to induce endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Subsequent Nectin-3 activity adds strength to the junction through trans-interaction with a variety of molecules. Recombinant human NECTIN3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    39.1kDa (355aa) 40-57kDa (SDS-PAGE under reducing conditions)
    NCBI登录号
    NP_056295
    UniProt
    Q9NQS3
    途径
    Cell-Cell Junction Organization
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