nectin-3 Protein (AA 58-400) (Fc Tag)
-
- 抗原 See all nectin-3 (NECTIN3) 蛋白
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 58-400
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This nectin-3 protein is labelled with Fc Tag.
- 应用范围
- Functional Studies (Func)
- 序列
- AA 58-400
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.3 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product NECTIN3 蛋白
-
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His-Avi Tag)
NECTIN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) protein (His-Avi Tag,Biotin)NECTIN3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag,AVI tag,Biotin)NECTIN3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) protein (GST tag)NECTIN3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 59-166) protein (GST tag)NECTIN3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 426-549) protein (His tag)Crystallography grade NECTIN3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Nectin cell adhesion molecule 3 (NECTIN3) (AA 426-549) protein (His tag)Crystallography grade NECTIN3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-404) protein (His tag)Crystallography grade NECTIN3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-404) protein (His tag)Crystallography grade NECTIN3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-549) protein (rho-1D4 tag)Crystallography grade NECTIN3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
- 抗原
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- 别名
- Nectin-3 (NECTIN3 产品)
- 别名
- PVRL3 Protein, CD113 Protein, CDW113 Protein, NECTIN-3 Protein, PPR3 Protein, PRR3 Protein, PVRR3 Protein, 2610301B19Rik Protein, 3000002N23Rik Protein, 4921513D19Rik Protein, AA407785 Protein, AU016832 Protein, AW538082 Protein, nectin cell adhesion molecule 3 Protein, poliovirus receptor-related 3 Protein, Nectin3 Protein, NECTIN3 Protein, PVRL3 Protein, nectin3 Protein
- 背景
- Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin system in epithelial cells. PVRL3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Furthermore, PVRL3 induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.
- 分子量
- 64.3 kDa
- UniProt
- Q9NQS3
- 途径
- Cell-Cell Junction Organization
-
