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OGG1 Protein (AA 1-345) (His tag)
OGG1
宿主: 小鼠
宿主: 大肠杆菌(E. Coli)
Recombinant
> 90 % by SDS - PAGE
SDS
产品细节
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抗原
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OGG1
(8-Oxoguanine DNA Glycosylase (OGG1))
蛋白类型
Recombinant
产品特性
AA 1-345
宿主
All origins for OGG1 蛋白
小鼠
资源
All sources for OGG1 蛋白
大肠杆菌(E. Coli)
标记
This OGG1 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
序列
MGSSHHHHHH SSGLVPRGSH MGSMLFRSWL PSSMRHRTLS SSPALWASIP CPRSELRLDL VLASGQSFRW KEQSPAHWSG VLADQVWTLT QTEDQLYCTV YRGDDSQVSR PTLEELETLH KYFQLDVSLA QLYSHWASVD SHFQRVAQKF QGVRLLRQDP TECLFSFICS SNNNIARITG MVERLCQAFG PRLIQLDDVT YHGFPNLHAL AGPEAETHLR KLGLGYRARY VRASAKAILE EQGGPAWLQQ LRVAPYEEAH KALCTLPGVG AKVADCICLM ALDKPQAVPV DVHVWQIAHR DYGWHPKTSQ AKGPSPLANK ELGNFFRNLW GPYAGWAQAV LFSADLRQPS LSREPPAKRK KGSKRPEG
纯度
> 90 % by SDS - PAGE
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 30 % glycerol
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
OGG1
(8-Oxoguanine DNA Glycosylase (OGG1))
别名
Ogg1 (OGG1 产品 )
别名
OGG1 Protein, zgc:158858 Protein, 8-oxoguanine-DNA glycosylase 1 Protein, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein, ATOGG1 Protein, F8K7.14 Protein, F8K7_14 Protein, 19.m02329 Protein, DDBDRAFT_0184479 Protein, DDBDRAFT_0233024 Protein, DDB_0184479 Protein, DDB_0233024 Protein, ogg1 Protein, Tb04.1H19.930 Protein, HMMH Protein, HOGG1 Protein, MUTM Protein, OGH1 Protein, Mmh Protein, 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA glycosylase L homeolog Protein, 8-oxoguanine-DNA glycosylase 1 Protein, 8-OXOGUANINE DNA GLYCOSYLASE Protein, putative 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA-glycosylase Protein, N-glycosylase/DNA lyase OGG1 Protein, 8-oxoguanine DNA-glycosylase 1 Protein, OGG1 Protein, ogg1.L Protein, ogg1 Protein, ECU08_0770 Protein, CA_C2707 Protein, BBOV_I004290 Protein, Smp_074010.1 Protein, LOC9329243 Protein, Tb927.4.2480 Protein, Ogg1 Protein
背景
Ogg1, also known as N-glycosylase/DNA lyase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3 to the lesion. Recombinant mouse Ogg1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
分子量
41.3 kDa (368aa) Confirmed by MALDI-TOF
NCBI登录号
NP_035087
UniProt
O08760
途径
DNA Damage Repair
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OGG1 蛋白
OGG1 Protein (AA 1-345) (His tag) (ABIN6388043)