OGG1 Protein (AA 1-345) (GST tag)
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- 抗原 See all OGG1 蛋白
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-345
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This OGG1 protein is labelled with GST tag.
- 原理
- Recombinant Human N-Glycosylase/OGG1 (N-GST)
- 序列
- MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSMPAR ALLPRRMGHR TLASTPALWA SIPCPRSELR LDLVLPSGQS FRWREQSPAH WSGVLADQVW TLTQTEEQLH CTVYRGDKSQ ASRPTPDELE AVRKYFQLDV TLAQLYHHWG SVDSHFQEVA QKFQGVRLLR QDPIECLFSF ICSSNNNIAR ITGMVERLCQ AFGPRLIQLD DVTYHGFPSL QALAGPEVEA HLRKLGLGYR ARYVSASARA ILEEQGGLAW LQQLRESSYE EAHKALCILP GVGTKVADCI CLMALDKPQA VPVDVHMWHI AQRDYSWHPT TSQAKGPSPQ TNKELGNFFR SLWGPYAGWA QAVLFSADLR QSRHAQEPPA KRRKGSKGPE G
- 产品特性
- Recombinant Human N-Glycosylase/DNA Lyase is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly345) of Human DNA Lyase fused with a GST tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product OGG1 蛋白
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8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) protein (His tag)
OGG1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) protein (His tag)OGG1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-324) protein (GST tag)OGG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
8-Oxoguanine DNA Glycosylase (OGG1) (AA 246-345) protein (GST tag)OGG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) protein (Strep Tag)Crystallography grade OGG1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) protein (Strep Tag)Crystallography grade OGG1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 1 mM EDTA, 50 % Glycerol, pH 7.8.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- 别名
- N-Glycosylase/DNA Lyase (OGG1 产品)
- 别名
- OGG1 Protein, zgc:158858 Protein, 8-oxoguanine-DNA glycosylase 1 Protein, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein, ATOGG1 Protein, F8K7.14 Protein, F8K7_14 Protein, 19.m02329 Protein, DDBDRAFT_0184479 Protein, DDBDRAFT_0233024 Protein, DDB_0184479 Protein, DDB_0233024 Protein, ogg1 Protein, Tb04.1H19.930 Protein, HMMH Protein, HOGG1 Protein, MUTM Protein, OGH1 Protein, Mmh Protein, 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA glycosylase L homeolog Protein, 8-oxoguanine-DNA glycosylase 1 Protein, 8-OXOGUANINE DNA GLYCOSYLASE Protein, putative 8-oxoguanine DNA glycosylase Protein, 8-oxoguanine DNA-glycosylase Protein, N-glycosylase/DNA lyase OGG1 Protein, 8-oxoguanine DNA-glycosylase 1 Protein, OGG1 Protein, ogg1.L Protein, ogg1 Protein, ECU08_0770 Protein, CA_C2707 Protein, BBOV_I004290 Protein, Smp_074010.1 Protein, LOC9329243 Protein, Tb927.4.2480 Protein, Ogg1 Protein
- Sub Type
- Fusionprotein
- 背景
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Human N-Glycosylase/DNA Lyase is a DNA repair enzyme, which incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. DGG1 has a beta-lyase activity that nicks DNA 3’ to the lesion.
Alternative Names: N-Glycosylase/DNA Lyase, 8-Oxoguanine DNA Glycosylase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, OGG1, MMH, MUTM, OGH1 - 分子量
- 65.07 kDa
- UniProt
- O15527
- 途径
- DNA Damage Repair
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