TDP1 Protein (AA 1-608) (His tag)
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- 抗原 See all TDP1 蛋白
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-608
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This TDP1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ADPMSQEGDY GRWTISSSDE SEEEKPKPDK PSTSSLLCAR QGAANEPRYT CSEAQKAAHK RKISPVKFSN TDSVLPPKRQ KSGSQEDLGW CLSSSDDELQ PEMPQKQAEK VVIKKEKDIS APNDGTAQRT ENHGAPACHR LKEEEDEYET SGEGQDIWDM LDKGNPFQFY LTRVSGVKPK YNSGALHIKD ILSPLFGTLV SSAQFNYCFD VDWLVKQYPP EFRKKPILLV HGDKREAKAH LHAQAKPYEN ISLCQAKLDI AFGTHHTKMM LLLYEEGLRV VIHTSNLIHA DWHQKTQGIW LSPLYPRIAD GTHKSGESPT HFKADLISYL MAYNAPSLKE WIDVIHKHDL SETNVYLIGS TPGRFQGSQK DNWGHFRLKK LLKDHASSMP NAESWPVVGQ FSSVGSLGAD ESKWLCSEFK ESMLTLGKES KTPGKSSVPL YLIYPSVENV RTSLEGYPAG GSLPYSIQTA EKQNWLHSYF HKWSAETSGR SNAMPHIKTY MRPSPDFSKI AWFLVTSANL SKAAWGALEK NGTQLMIRSY ELGVLFLPSA FGLDSFKVKQ KFFAGSQEPM ATFPVPYDLP PELYGSKDRP WIWNIPYVKA PDTHGNMWVP SHHHHHH
- 纯度
- > 90 % by SDS - PAGE
- 内毒素水平
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product TDP1 蛋白
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Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) protein (GST tag)
TDP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 121-218) protein (GST tag)TDP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) proteinTDP1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, ELISA, IP
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TDP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TDP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 别名
- TDP1 (TDP1 产品)
- 别名
- 2810481F14Rik Protein, 4921509N21Rik Protein, AI838772 Protein, AW493413 Protein, E430034L06Rik Protein, MLZ-501 Protein, SCAN1 Protein, tdp1 Protein, MGC83708 Protein, TDP1 Protein, F8M21.60 Protein, F8M21_60 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA phosphodiesterase 1 Protein, tyrosyl-DNA Phosphodiesterase (Tdp1) Protein, tyrosyl-DNA phosphodiesterase 1 L homeolog Protein, tyrosyl-DNA phosphodiesterase-like protein Protein, TDP1 Protein, Tc00.1047053511191.10 Protein, Tdp1 Protein, tdp1.L Protein, tdp1 Protein, PTRG_11198 Protein, MCYG_02121 Protein, MGYG_03035 Protein
- 背景
- TDP1, also known as tyrosyl-DNA phosphodiesterase 1, is involved in repairing stalled topoisomerase l-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase l and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical meditated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 69.5kDa (617aa) 50-70kDa (SDS-PAGE under reducing conditions.)
- NCBI登录号
- NP_060789
- UniProt
- Q9NUW8
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